Recombinant CD22 anticorps
Aperçu rapide pour Recombinant CD22 anticorps (ABIN7795341)
Antigène
Voir toutes CD22 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Expression System
- Mammalian cells
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Fonction
- Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971), Human IgG1 Fc Silent Kappa
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Attributs du produit
- The recombinant NCI m971 antibody binds to the human CD22 protein, a sugar binding transmembrane protein, which specifically binds sialic acid with an immunoglobulin (Ig) domain located at its N-terminus. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice. In mice, it has been shown that CD22 blockade restores homeostatic microglial phagocytosis in aging brains.
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Purification
- Protein A or G affinity column
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Pureté
- >95 % by reducing SDS-PAGE
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Isotype
- Fc Silenced, IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- > 3 mg/mL
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- CD22 (CD22 Molecule (CD22))
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Autre désignation
- Siglec-2/CD22
Antigène
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